Center for Adaptive Optical Microscopy

W.M. Keck Center for Adaptive Optical Microscopy

Welcome to the W.M. Keck Center for Adaptive Optical Microscopy. This Center was made possible through the generous support of the W.M. Keck Foundation. The following publications describe the work that is ongoing in the Center.

Journal Articles

  1. Xiaodong Tao, Ziah Dean, Christopher Chien, Oscar Azucena, Dare Bodington, and Joel Kubby, Shack-Hartmann wavefront sensing using interferometric focusing of light onto guide-stars, Optics Express Vol. 21, Iss. 25, pp. 31282–31292 (2013). (Link to PDF).
  2. Xiaodong Tao, Andrew Norton, Matthew Kissel, Oscar Azucena, and Joel Kubby, Adaptive optical two-photon microscopy using autofluorescent guide stars, Optics Letters Vol. 38, Iss. 23, pp. 5075–5078 (2013). (Link to PDF).
  3. Bautista R. Fernández ; Mohamed Amine Bouchti ; Joel Kubby, High-stroke, high-order MEMS deformable mirrors, J. Micro/Nanolith. MEMS MOEMS 12, p. 33012 (2013). (Link to PDF).
  4. Xiaodong Tao, Justin Crest, Shaila Kotadia, Oscar Azucena, Diana C. Chen, William Sullivan, and Joel Kubby, Live imaging using adaptive optics with fluorescent protein guide-stars, Optics Express 20, pp. 15969-15982 (2012). (Link to PDF) Movie 1, Movie 2, Movie 3, Movie 4.
  5. Xiaodong Tao, Oscar Azucena, Min Fu, Yi Zuo, Diana C. Chen, and Joel Kubby, Adaptive optics microscopy with direct wavefront sensing using fluorescent protein guide stars, Optics Letters Vol. 36, Issue 17, pp. 3389–3391 (2011). (Link to PDF).
  6. Tao, Xiaodong; Fernandez, Bautista; Azucena, Oscar; Fu, Min; Garcia, Denise; Zuo, Yi; Chen, Diana C; Kubby, Joel, Adaptive optics confocal microscopy using direct wavefront sensing, Optics Letters, Vol. 36 Issue 7, pp.1062-1064 (2011). (Link to PDF).
  7. Azucena, Oscar; Crest, Justin; Kotadia, Shaila; Sullivan, William; Tao, Xiaodong; Reinig, Marc; Gavel, Donald; Olivier, Scot; Kubby, Joel, Adaptive optics wide-field microscopy using direct wavefront sensing, Optics Letters, Vol. 36 Issue 6, pp.825-827 (2011). (Link to PDF).
  8. Oscar Azucena, Justin Crest, Jian Cao, William Sullivan, Peter Kner, Donald Gavel, Daren Dillon, Scot Olivier, Joel Kubby, Wavefront aberration measurements and corrections through thick tissue using fluorescent microsphere reference beacons, Optics Express 18, Issue 16, pp. 17521-17532 (2010). (Link to PDF).
  9. Bautista R. Fernández and Joel Kubby, High-aspect-ratio microelectromechanical systems deformable mirrors for adaptive optics, J. Micro/Nanolith. MEMS MOEMS 9, p. 041106 (2010). (Link to PDF).

Conference Proceedings

  1. Xiaodong Tao, Andrew Norton, Matthew Kissel, Oscar Azucena and Joel Kubby, Adaptive optics two photon microscopy with direct wavefront sensing using autofluorescent guide-stars, Proceedings of the SPIE, Volume XXXX, pp. XXX (2014). (Link to PDF).
  2. Matthew Kissel, Marc Reinig, Oscar Azucena, Juan J. Díaz León, Joel Kubby, Development and testing of an AO-structured illumination microscope, Proceedings of the SPIE, Volume XXXX, pp. XXX (2014). (Link to PDF).
  3. Xiaodong Tao; Ziah Dean; Christopher Chien; Oscar A. Azucena, Jr.; Joel Kubby, Interferometric focusing of guide-stars for direct wavefront sensing, Proc. SPIE 8617, p. 86170E (2013). (Link to PDF).

  4. Xiaodong Tao, Oscar Azucena, Min Fu, Yi Zuo, Diana C. Chen, Joel Kubby, Adaptive optics confocal microscopy using fluorescent protein guide-stars for brain tissue imaging, Proc. SPIE 8253, pp. 82530M-82530M-6 (2012). (Link to PDF)
  5. Oscar Azucena, Xiaodong Tao, Justin Crest, Shaila Kotadia, William Sullivan, Donald Gavel, Marc Reinig, and Joel Kubby, Adaptive optics wide-field microscope corrections using a MEMS DM and Shack-Hartmann wavefront sensor, Proc. SPIE 7931, 79310J (2011). DOI:10.1117/12.876439 (Link to PDF)
  6. Tao, Xiaodong; Fernandez, Bautista; Chen, Diana C.; Azucena, Oscar; Fu, Min; Zuo, Yi; Kubby, Joel, Adaptive optics confocal fluorescence microscopy with direct wavefront sensing for brain tissue imaging, Proceedings of the SPIE, Volume 7931, pp. 79310L-79310L-8 (2011). DOI: 10.1117/12.876524 (Link to PDF)
  7. Azucena, Oscar; Crest, Justin; Cao, Jian; Sullivan, William; Kner, Peter; Gavel, Donald; Dillon, Daren; Olivier, Scot; Kubby, Joel, Implemenation of adaptive optics in fluorscent microscopy using wavefront sensing and correction, MEMS Adaptive Optics IV. Edited by Olivier, Scot S.; Bifano, Thomas G.; Kubby, Joel A. Proceedings of the SPIE, Volume 7595, pp. 75950I-75950I-9 (2010). (Link to PDF).
  8. Oscar Azucena; Joel Kubby; Justin Crest; Jian Cao; William Sullivan; Peter Kner; Donald Gavel; Daren Dillon; Scot Olivier, Implementation of a Shack-Hartmann wavefront sensor for the measurement of embryo-induced aberrations using fluorescent microscopy, Proc. SPIE 7209, p. 720906 (2009). (Link to PDF).

Books & Chapters

  1. Adaptive Optics for Biological Imaging, Edited by Joel. A. Kubby, CRC Press, Taylor & Francis Group, Boca Raton, FL (2013). (Link to Book).
  2. Principles of Geometric Optics, Joel Kubby in Adaptive Optics for Biological Imaging, Edited by Joel. A. Kubby, CRC Press, Taylor & Francis Group, Boca Raton, FL (2013). (Link to Chapter).
  3. Wavefront Correctors, Joel Kubby in Adaptive Optics for Biological Imaging, Edited by Joel. A. Kubby, CRC Press, Taylor & Francis Group, Boca Raton, FL (2013). (Link to Chapter).
  4. Adaptive Optical Microscopy using Direct Wavefront Sensing, Oscar Azucena, Xiaodong Tao and Joel Kubby in Adaptive Optics for Biological Imaging, Edited by Joel. A. Kubby, CRC Press, Taylor & Francis Group, Boca Raton, FL (2013). (Link to Chapter).
  5. Adaptive Optics Wide-Field Microscopy using Direct Wavefront Sensing (Link to Thesis).
  6. Design, Construction, and On-sky Performance of a MEMS-based Uplink-Adaptive Optics System (Link to Thesis)

Patents

  1. Use of a reference source with adaptive optics in biological microscopy. (Link to PDF).

Press Articles

  1. Detection, W.M. Keck Foundation 2012 Annual Report. (Link to PDF).

  2. Scintillating Science, International Innovation, Healthcare 15, p. 121 (2012). (Link ro PDF).

  3. Justin Crest, Shaila Kotadia, andWilliam Sullivan, Telescopes, stars, and cells: adaptive optics microscopy, SPIE Newsroom (2011). (Link to PDF).

  4. Adam Mann, Twinkle, twinkle little cell, (2010). (Link to PDF).

Webinars

  1. Adaptive Optics for Microscopy (Link to webinar), (Link to slides).